Calreticulin Blockade Attenuates Murine Acute Lung Injury by Inducing Polarization of M2 Subtype Macrophages
Calreticulin (CALR) has anti-tumor effects by increasing dendritic cell maturation and tumor antigen presentation.However, whether CALR affects macrophages and modulates progression of acute respiratory distress syndrome/acute lung injury (ARDS/ALI) remains unknown.In this study, we discovered that CALR protein was highly expressed in the mice with